Non-stop* antibacterial action for a full 12 hours with the Dual-Zinc + Arginine technology of Colgate Total

*with 2x daily brushing and 4 weeks continued use.
† Fluorescent microscopy images of in vitro study. Bacterial biofilms treated for 2-minutes with non-antibacterial fluoride or Dual-Zinc + Arginine toothpaste slurry, followed by a 12-hour regrowth period.
‡ Defined as a non-antibacterial fluoride toothpaste. Some bacteria are mechanically removed while brushing.
§ Statistically significant greater reduction of cultivable bacteria on teeth, tongue, cheeks and gums with Colgate Total® vs non-antibacterial fluoride toothpaste at 4 weeks, 12 hours after brushing.
-
Superior bacterial reductions
*with 2x daily brushing and 4 weeks continued use.
†Colgate Total® provides superior in vitro delivery, penetration and retention of Zinc through Arginine technology for biomass reductions vs Zinc control toothpaste
‡ Defined as a non-antibacterial fluoride toothpaste. Some bacteria are mechanically removed while brushing.
References: 1. Daep C, et al. August 2019. Data on file. 2. Manus L, et al. J Clin Dent. 2018;29(Spec lss A)A10-19. 3. Manus L, et al. 2021 IADR/AADR/CADR General Session. 4. Prasad K, et al. J Clin Dent. 2018;29(Spec lss A):A 25-3. -
Protection from biofilm damage
Evidence on how non-stop* antibacterial action protects the mouth from biofilm damage
*with 2x daily brushing and 4 weeks continued use.
References: 1. Makwana E, et al. J Dent Res. 2019;98(Spec lss A):3202. 2. Manus L, et al. 2021 IADR/AADR/CADR General Session. 3. Prasad K, et al. J Clin Dent. 2018;29(Spec lss A):A25-3. -
More superior outcomes
*Statistically significant reductions vs non-antibacterial fluoride toothpaste (p<0.001).
† After 8 weeks.
‡ Colgate Total® Pro Gum Health Whitening 1450ppm fluoride toothpaste.
§ Statistically significant reduction vs non-antibacterial ordinary fluoride toothpaste 12 hours overnight with continuous use for 3 weeks.
References: 1. Delgado E, et al. J Clin Dent. 2018;29(Spec lss A)A10-19. 2. Seriwatanachai & Mateo, September 2016, internal report. 3. Hu D, et al. J Clin Dent. 2018;29(Spec lss A)A41 -45.