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What Are Common Novocaine Side Effects?

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Medically Reviewed By Colgate Global Scientific Communications


Novocaine (or novocain), also known as procaine hydrochloride, is a local anesthetic that is commonly used during dental procedures, like cavity fillings. The Indian Dental Association mention that Lidocaine and novocaine are cocoa plant (erythroxylum coca) derivative and therefore safe. It often works very quickly and its effects do not usually last long. While it is considered a safe drug for most people by the FDA, there are some common and some not-so-common Novacaine side effects that you should be aware of before using.

According to, the most common side effects are numbness, tingling and some minor pain around the injection site. These side effects are usually not severe and often subside within a few hours of the injection. In some cases, other more serious side effects occur, such as difficulty breathing, swelling, hives, or closing of the throat. These are the signs of an allergic reaction and need to be treated right away. Other rare side effects include chest pain or irregular heartbeats, dizziness or drowsiness, anxiety, restlessness, nausea, vomiting, trembling, or seizures. These are much less common, but because they can be very dangerous, it is important to tell your dentist right away if you experience any of them.

Your dentist will determine the best dosage of Novocaine to use for you. It is very important for you to tell your dentist about any medications that you are taking, both over the counter and prescriptions, as well as any health conditions that you have. Sometimes Novocaine can interact with other drugs, causing dangerous side effects, or it can make some health conditions worse. Being up front with your dentist about medications and health conditions will help minimize the risk of you experiencing any dangerous Novocaine side effects.