Novocaine (or novocain), also known as procaine hydrochloride, is a local anesthetic that is commonly used during dental procedures, like cavity fillings. The Indian Dental Association mention that Lidocaine and novocaine are cocoa plant (erythroxylum coca) derivative and therefore safe. It often works very quickly and its effects do not usually last long. While it is considered a safe drug for most people by the FDA, there are some common and some not-so-common Novacaine side effects that you should be aware of before using.