The phrase "smiling through the pain" takes on new meaning for patients of angular Cheilitis. Also known as perlèche, angular stomatitis, or cheilosis, angular Cheilitis describes the inflammation and dry, cracked skin at one or both corners of the mouth. Suppose the patient opens their mouth too wide. In that case, the skin can split and bleed, making eating, talking, and even smiling uncomfortable. But what causes this painful condition, and — more importantly — how can you find relief?