Prescription Products

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At Colgate, we understand that some smiles need extra support. For individuals with specific oral health needs, prescription toothpaste can play a vital role in achieving and maintaining dental health. Our range of prescription toothpaste solutions is developed with advanced science and trusted by dental professionals to deliver targeted care when you need it most.

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Colgate PreviDent PP Packshot_Front

Colgate® PreviDent® Rinse (0.2% Neutral Sodium Fluoride), Mint

Colgate® PreviDent® Oral Rinse is prescription-strength, with extra fluoride to help decrease cavities for people who have trouble brushing.

Colgate Gel-Kam HF PP Packshot_Front

Colgate® Gel-Kam® Preventive Treatment Gel, Mint

Colgate® Gel-Kam Preventative Treatment Gel prevents cavities and treats sensitive teeth with a clinically proven fluoride formula. Try it today!

Colgate PreviDent Varnish HF PP Packshot_Front

Colgate® PreviDent® Varnish (5% Sodium Fluoride), Raspberry

Colgate® PreviDent® Varnish is an in-office treatment for sensitive teeth. Contact your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 ppm Kids (1.1% Sodium Fluoride)

Help pepare children's smiles for the future. Colgate® PreviDent® 5000 Kids Prescription Toothpaste is a prescription strength fluoride toothpaste trusted by dental professionals. Contact your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 ppm Enamel Protect (1.1% Sodium Fluoride, 5% Potassium Nitrate), Mint

Colgate® PreviDent® 5000 Enamel Protection is a high fluoride toothpaste formulated to strengthen teeth & enamel for a healthier smile. Contact your your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 ppm Dry Mouth (1.1% Sodium Fluoride), Soothing Mint

Colgate® PreviDent® 5000 Dry Mouth is a prescription strength toothpaste to fight dry mouth and remineralize teeth. Contact your your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 ppm Sensitive (1.1% Sodium Fluoride, 5% Potassium Nitrate), Mild Mint

Colgate® PreviDent® 5000 Sensitive Protection is a low abrasion, prescription strength toothpaste for sensitive teeth and Prevents Cavities. Ask your dentist!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® Gel (1.1% Sodium Fluoride), Very Berry

Colgate® PreviDent® Gel is an at-home, Rx Only brush-on gel treatment for those that require extra-strength fluoride protection. Contact your your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 ppm Kids (1.1% Sodium Fluoride)

Help pepare children's smiles for the future. Colgate® PreviDent® 5000 Kids Prescription Toothpaste is a prescription strength fluoride toothpaste trusted by dental professionals. Contact your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 Plus (1.1% Sodium Fluoride), Spearmint

Colgate® PreviDent® 5000 Plus Prescription Toothpaste delivers 4x the fluoride than over-the-counter toothpastes & rinses. Contact your your dentist today!

Colgate PreviDent Toothpaste HF PP Packshot_Front

Colgate® PreviDent® 5000 ppm Booster Plus (1.1% Sodium Fluoride), Spearmint

Colgate® PreviDent® 5000 Booster Plus is a high fluoride prescription strength toothpaste for unsurpassed remineralization. Contact your your dentist today!

Your Partner in Specialized Oral Care

Colgate works closely with dental professionals to ensure that patients receive the highest standard of care. If you think you may benefit from prescription toothpaste, talk to your dentist about your specific needs and explore our full range of advanced oral care solutions. Together, we can help you achieve strong, healthy teeth and a bright smile.

Prescription Toothpaste Frequently Asked Questions

Prescription toothpaste is specially formulated to address oral health concerns that go beyond what over-the-counter products can provide. Whether you’re managing tooth sensitivity, high risk of cavities, our prescription toothpaste offers higher concentrations of active ingredients—such as fluoride—to provide enhanced protection and relief. These products are recommended by your dentist or healthcare provider and are designed to be an essential part of your personalized oral care plan.

 

Colgate’s prescription toothpaste options are backed by decades of research and innovation. Each formula is created to meet the unique needs of patients who require specialized oral care, offering benefits such as:

  • Cavity Prevention: prescription strength toothpaste that helps strengthen enamel and offer enhanced defense against tooth decay, especially for those at increased risk.

  • Sensitivity Relief: Prescription toothpaste formulas provide long-lasting relief from tooth sensitivity, helping you enjoy your favorite foods and drinks without discomfort.

As a global leader in oral health, Colgate is committed to delivering safe, effective, and scientific solutions for every stage of your oral care journey. Our prescription toothpaste products are rigorously tested for safety and efficacy, and are trusted by dental professionals worldwide. When you choose Colgate, you’re choosing a partner dedicated to your healthiest smile.

Always use prescription toothpaste exactly as directed by your dentist or healthcare provider. Avoid rinsing immediately after brushing to allow the active ingredients to work effectively. If you have questions about your prescription toothpaste regimen, consult your dental professional for personalized guidance.